Browsing by Author "Estrada Hormazábal, Manuel Iván"

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    • CaMKIId Splice variants in the healthy and diseased heart 
      Durán, Javier; Nickel, Lennart; Estrada Hormazábal, Manuel Iván; Backs, Johannes; Van den Hoogenhof, Maarten M. G. (Frontiers Media, 2021)
      RNA splicing has been recognized in recent years as a pivotal player in heart development and disease. The Ca2C/calmodulin dependent protein kinase II delta (CaMKIId) is a multifunctional Ser/Thr kinase family and generates ...
    • Testosterone activates glucose metabolism through AMPK and androgen signaling in cardiomyocyte hypertrophy 
      Troncoso Magñin, Mayarling Francisca; Pavez Giani, Mario Gustavo; Wilson Rodríguez, Carlos Antonio; Lagos Cerón, Daniel Alejandro; Durán Gárate, Javier Andre; Ramos, Sebastián; Barrientos Briones, Genaro Christian; Silva, Patricio; Llanos Vidal, Paola Andrea; Basualto Alarcón, Carla Edith; Westenbrink, B. Daan; Lavandero González, Sergio Alejandro; Estrada Hormazábal, Manuel Iván (BMC, 2021)
      Background Testosterone regulates nutrient and energy balance to maintain protein synthesis and metabolism in cardiomyocytes, but supraphysiological concentrations induce cardiac hypertrophy. Previously, we determined that ...